Endocrine Abstracts

Background: There is convincing evidence that the increasing of visceral fat is a risk factor for vascular disease. Type 1 diabetes mellitus (T1DM) is characterized by the development of micro-, and later, and macrovascular complications. The aim of the study was to examine features of body composition fat distribution parameters in T1DM patients.Materials and methods: 96 patients with T1DM (59 women and 37 men) (mean age: 32.52±10.71 years, duratio...

Osteoporosis is a common skeletal disease characterized by low bone mass and microarchitectural deterioration with increased susceptibility to fracture. Osteoporosis has a complex etiology and is considered to be a multifactorial polygenic disease. There are more than 150 genes associated with bone mineral density. Our aim was to investigate the frequency of occurrence of vitamin D receptor (VDR) – (FokI, BsmI, ApaI, TaqI) – single nucleotide polymorphisms (SNPs) in ...

Objective: Patients with type 2 diabetes mellitus (DM) are expected to follow numerous dietary recommendations which can be difficult to adhere and that can cause changes in their eating behavior. Few studies have examined prevalence rates eating disorders in adults with type 2 DM despite the fact that DM is highly correlated with overweight and obesity. The aim of the study was to assess the prevalence of disordered eating behavior in type 2 diabetes mellitus patients receive...

IntroductionGhrelin has an important role in insulin resistance, glucose and lipid metabolism and cardiovascular morbidity and mortality. It is still unclear whether insulin and glucose per se play a direct inhibitory role in ghrelin secretion. The decrease in ghrelin levels after an oral glucose load is modulated by sex, status of obesity, and level of insulin resistance. The aim of our study was to evaluate gender differences in ghrelin levels in type ...

Currently relationship between the decrease in vitamin D (VD) levels and the formation of bone pathology has established. The presence of certain VD receptor (VDR) polymorphisms has been suggested to be associated with the serum VD. Therefore, the aim of study was to assess the association between VDR single nucleotide polymorphisms (SNPs) in type 1 diabetic patients and serum VD.Materials and methods: We studied 66 type 1 diabetic (T1D) patients (28 men...